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Extended Release Injectable Naltrexone for Treatment of Opioid Dependence

1. Which of the following factors may improve access to treatment for opioid dependence?

A. Naltrexone can be prescribed by any healthcare provider who is licensed to prescribe medications. B. Special training is not required; naltrexone can be administered in OTP clinics. C. Practitioners in community health centers or private office settings can prescribe naltrexone for purchase at the pharmacy. D. All of the above.

2. Naltrexone is a partial opioid agonist and therefore has mild abuse potential.

A. True B. False

3. Cases of fatal opioid overdose have been reported in patients who:

A. Used opioids at or near the end of the 1-month dosing interval. B. Used opioids after missing a dose of extended-release injectable naltrexone. C. Attempted to overcome the opioid blockade. D. All of the above.

4. If patients who are treated with extended-release injectable naltrexone relapse after a period of abstinence, it is possible that the dosage of opioid that was previously used may have life-threatening consequences, including respiratory arrest and circulatory collapse.

A. True B. False

5. At least _____ without opioid use is recommended before beginning extended-release injectable naltrexone.

A. 24 - 48 hours B. 3 - 4 days C. 7 - 10 days D. 14 days

6. Extended-release injectable naltrexone should be administered as a subcutaneous injection using the specially designed administration needle provided.

A. True B. False

7. Use of the medication is contraindicated in patients with:

A. Chronic kidney disease B. Acute hepatitis or liver failure C. Cardiovascular disease D. All of the above

8. All of the following people may be good candidates for treatment with naltrexone, except for:

A. People who have not had treatment success with methadone or buprenorphine. B. People who have a low level of motivation for abstinence. C. Adolescents or young adults with opioid dependence. D. People successful on agonists who wish to change their medication or patients not interested in agonist therapy to treat their opioid dependence.

9. For most patients with opioid dependence, medications alone are insufficient.

A. True B. False

10. Which of the following pertains to emergency situations?

A. It is possible for healthcare providers to reverse extended-release injectable naltrexone's opioid receptor blockade. B. Higher than usual dosages of a rapidly acting opioid medication may be needed to achieve pain relief if a patient still has a tolerance to opioids. C. Patients administered high doses of opioid medication should be closely monitored by professionals trained in the use of anesthetic drugs, management of respiratory depression, and the performance of cardiopulmonary resuscitation. D. All of the above.


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